BDBM50283974 CHEMBL152784::N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzothiepin-4-yl)methyl]urea

SMILES NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2SCC1

InChI Key InChIKey=PSDGROBAPRJBMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283974   

LigandPNGBDBM50283974(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzothiepin...)
Affinity DataIC50: 120nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283974(N-hydroxy-N-[(7-phenoxy-2,3-dihydro-1-benzothiepin...)
Affinity DataIC50: 130nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article