BDBM50283973 CHEMBL150385::N-hydroxy-N-[(8-phenoxy-2,3-dihydro-1-benzoxepin-4-yl)methyl]urea

SMILES NC(=O)N(O)CC1=Cc2ccc(Oc3ccccc3)cc2OCC1

InChI Key InChIKey=LWAAKDAFNRYRTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283973   

LigandPNGBDBM50283973(N-hydroxy-N-[(8-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 210nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283973(N-hydroxy-N-[(8-phenoxy-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 180nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article