BDBM50283777 BDBM50284761::CHEMBL295022::CHEMBL32248::[1-(1-Carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-carbamic acid benzyl ester

SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1

InChI Key InChIKey=MOFIHHRIGQKWJP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50283777   

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50283777(CHEMBL32248 | BDBM50284761 | [1-(1-Carbamoyl-2-phe...)
Affinity DataIC50: 5.20E+3nMAssay Description:Binding affinity towards Tachykinin receptor 2 using [125I]iodohistidyl-NKA (0.1 nM)) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283777(CHEMBL32248 | BDBM50284761 | [1-(1-Carbamoyl-2-phe...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against binding of [125I]-Bolton-Hunter SP to tachykinin NK-1 receptor in human lymphoma IM9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetNeuromedin-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283777(CHEMBL32248 | BDBM50284761 | [1-(1-Carbamoyl-2-phe...)
Affinity DataIC50: 9.30E+3nMAssay Description:Binding affinity towards Tachykinin receptor 3 using [125I]-[Mephe7] NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283777(CHEMBL32248 | BDBM50284761 | [1-(1-Carbamoyl-2-phe...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of [125I]BH-SP binding to tachykinin NK1 receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article