BDBM50283690 CHEMBL4165199

SMILES FC(F)(F)c1cc(ccc1Cl)-n1ccc(=O)c(n1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1

InChI Key InChIKey=HNBIYJXTHLOAMC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50283690   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50283690(CHEMBL4165199)
Affinity DataIC50: 770nMAssay Description:Inhibition of FLT3 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50283690(CHEMBL4165199)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50283690(CHEMBL4165199)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50283690(CHEMBL4165199)
Affinity DataIC50: 73nMAssay Description:Inhibition of c-MET (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shift...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50283690(CHEMBL4165199)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition by mobility shif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed