BDBM50282975 Benzoic acid 1-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butyl ester::CHEMBL57297

SMILES Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(F)cn1)OC(=O)c1ccccc1

InChI Key InChIKey=MRYSLFOELZNLKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282975   

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282975(Benzoic acid 1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50: 581nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50282975(Benzoic acid 1-(4-fluoro-phenyl)-4-[4-(5-fluoro-py...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro binding affinity towards sigma receptor by the displacement of [3H]PPP from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article