BDBM50282959 5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]-piperazin-1-yl}-pyrimidine::CHEMBL61304

SMILES Fc1cnc(nc1)N1CCN(CCCCc2ccc(F)c3ccccc23)CC1

InChI Key InChIKey=CREVRAFFOUPVBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282959   

LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50: 213nMAssay Description:In vitro binding affinity towards sigma receptor by the displacement of [3H]PPP from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 1A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50: 414nMAssay Description:In vitro binding affinity towards serotonin 5-HT1A receptor by the displacement of [3H]8-OH-DPAT from rat hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

Target5-hydroxytryptamine receptor 2A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282959(5-Fluoro-2-{4-[4-(4-fluoro-naphthalen-1-yl)-butyl]...)
Affinity DataIC50: 590nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor by the displacement of [3H]spiperone from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article