BDBM50282857 1-[2-((S)-3-Mercapto-2-methyl-propionylamino)-propionyl]-pyrrolidine-2-carboxylic acid::CHEMBL440856

SMILES C[C@H](CS)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H]1C(O)=O

InChI Key InChIKey=HIHREGWKLSZLHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282857   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282857(1-[2-((S)-3-Mercapto-2-methyl-propionylamino)-prop...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282857(1-[2-((S)-3-Mercapto-2-methyl-propionylamino)-prop...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article