BDBM50282846 (S)-1-[(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptomethyl-3-phenyl-propionylamino)-propionyl]-pyrrolidine-2-carboxylic acid::CHEMBL50954

SMILES OC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CS)Cc1ccccc1

InChI Key InChIKey=ZSLOSCKFJWHNAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282846   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282846((S)-1-[(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptometh...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensin-converting enzyme(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282846((S)-1-[(S)-3-(1H-Indol-3-yl)-2-((S)-2-mercaptometh...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article