BDBM50282735 4'-(4-Oxo-2-propyl-8-thia-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-sulfonic acid benzoylamide::CHEMBL39996

SMILES CCCC1=NC2(CCSCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1

InChI Key InChIKey=PYPOKAAQTCYXDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282735   

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282735(4'-(4-Oxo-2-propyl-8-thia-1,3-diaza-spiro[4.5]dec-...)
Affinity DataIC50: 200nMAssay Description:The compound was tested for the ability to displace 50% of totally specifically bound [125I]- Ang II from Angiotensin II receptor, type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282735(4'-(4-Oxo-2-propyl-8-thia-1,3-diaza-spiro[4.5]dec-...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]- Ang II from type 1 Angiotensin II receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article