BDBM50282706 CHEMBL276853::N-{2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-N-(3-methyl-but-2-enyl)-benzamide

SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(CC=C(C)C)C(=O)c1ccccc1

InChI Key InChIKey=ALZKZYQRFDKNDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282706   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50282706(N-{2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 79nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50282706(N-{2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 1nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetAngiotensinogen(Rat)
Mnr College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50282706(N-{2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 0.460nMAssay Description:Binding affinity to AT2 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed