BDBM50282619 CHEMBL4159902

SMILES Nc1ccc(O)c2ccncc12

InChI Key InChIKey=BCIFJDGSMDSLLM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50282619   

TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50282619(CHEMBL4159902)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50282619(CHEMBL4159902)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of KAT2B catalytic domain (492 to 658 residues) (unknown origin) using H-ARTKQTARKSTGGKAPRKQL-OH as substrate after 5 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50282619(CHEMBL4159902)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of KAT3B catalytic domain (1284 to 1673 residues) (unknown origin) using SGRGKGGKGLGKGGAKRHRK-NH2 as substrate after 5 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed