BDBM50282516 3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonate::Benzenesulfonic acid 3,4-dimethyl-2-oxo-2H-chromen-7-yl ester::CHEMBL18978

SMILES Cc1c(C)c(=O)oc2cc(OS(=O)(=O)c3ccccc3)ccc12

InChI Key InChIKey=FMWFBKVHLXWFOF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50282516   

LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 75.9nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50282516(3,4-dimethyl-2-oxo-2H-chromen-7-yl benzenesulfonat...)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed