BDBM50282514 3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one::CHEMBL18966

SMILES Cc1ccc(COc2ccc3c(C)c(C)c(=O)oc3c2)cc1

InChI Key InChIKey=GXFXMBTYRNXLMV-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50282514   

LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 0.900nMAssay Description:In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 560nMAssay Description:In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibitory activity against monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 6.20nMAssay Description:Inhibitory activity against monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 6.17nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 6.17nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 1.38nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Babu Banarasi Das Northern India Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50282514(3,4-dimethyl-7-(4-methyl-benzyloxy)-chromen-2-one ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine chloride as substrate incubated for 5 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed