BDBM50282489 1-Naphthylamine::CHEBI:50450::CHEMBL57394::Naphthalen-1-ylamine

SMILES c1ccc2c(c1)cccc2N

InChI Key InChIKey=RUFPHBVGCFYCNW-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282489   

TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50282489(CHEBI:50450 | 1-Naphthylamine | Naphthalen-1-ylami...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50282489(CHEBI:50450 | 1-Naphthylamine | Naphthalen-1-ylami...)
Affinity DataKd:  1.20E+6nMAssay Description:Binding affinity to human recombinant His-tagged Keap1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissoc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed