BDBM50282164 CHEMBL4164708

SMILES COC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCC(N)=O

InChI Key InChIKey=AETJYYFBSYAFDG-UHFFFAOYSA-O

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282164   

TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282164(CHEMBL4164708)
Affinity DataKd:  8.80E+3nMAssay Description:Binding affinity to full length N-terminal His-tagged EED (unknown origin) expressed in Rosetta2 BL21(DE3)pLysS cells by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282164(CHEMBL4164708)
Affinity DataKd:  8.80E+3nMAssay Description:Binding affinity to N-terminal His-tagged full length EED (unknown origin) expressed in Escherichia coli Rosetta2 BL21(DE3)pLysS by isothermal titrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282164(CHEMBL4164708)
Affinity DataIC50: 1.48E+4nMAssay Description:Displacement of 3-FAM from N-terminal 6His-tagged full length EED (unknown origin) expressed in Escherichia coli Rosetta2 BL21(DE3)pLysS incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282164(CHEMBL4164708)
Affinity DataKd:  8.82E+3nMAssay Description:Binding affinity to N-terminal His-tagged full length EED (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed