BDBM50282161 CHEMBL4175336

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCC[N+](C)(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)C(N)=O

InChI Key InChIKey=ZZEFIZCWHLCWRV-UHFFFAOYSA-O

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282161   

TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282161(CHEMBL4175336)
Affinity DataKd:  1.09E+3nMAssay Description:Binding affinity to full length N-terminal His-tagged EED (unknown origin) expressed in Rosetta2 BL21(DE3)pLysS cells by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50282161(CHEMBL4175336)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length N-terminal His-tagged EED (unknown origin) expressed in Rosetta2 BL21(DE3)pLysS cells after 30 mins by 3-FAM labelled fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed