BDBM50281950 1-{2-Butyl-4-oxo-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-3-isopropyl-urea::CHEMBL25585

SMILES CCCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key InChIKey=ZYYSNXPYCJHCLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281950   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281950(1-{2-Butyl-4-oxo-3-[2'-(2H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 0.75nMAssay Description:Ability to displace [125I]Sar1-Ile8-AII from angiotensin II receptor, type 1 in rabbit aorta in presence of 0.2% bovine serum albumin (BSA) was deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281950(1-{2-Butyl-4-oxo-3-[2'-(2H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article