BDBM50281727 1-Naphthalen-1-yl-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1-yl-ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl]-urea::CHEMBL168386

SMILES O=C(CN1c2ccccc2CCC(NC(=O)Nc2cccc3ccccc23)C1=O)N1CCCC1

InChI Key InChIKey=DAHZFFGRUGCMMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281727   

LigandPNGBDBM50281727(1-Naphthalen-1-yl-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1...)
Affinity DataIC50: 650nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281727(1-Naphthalen-1-yl-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1...)
Affinity DataIC50: 1.70E+3nMAssay Description:Ability to inhibit the binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281727(1-Naphthalen-1-yl-3-[2-oxo-1-(2-oxo-2-pyrrolidin-1...)
Affinity DataIC50: 460nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article