BDBM50281711 1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-urea::CHEMBL169661

SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key InChIKey=NKXJTSZBOBZLTH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50281711   

LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 5.5nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type B receptor in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 12nMAssay Description:Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Tested for its activity to inhibit the binding of [125I]CCK-33 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50281711(1-(4-Chloro-phenyl)-3-((R)-1-methyl-2-oxo-5-phenyl...)
Affinity DataIC50: 12nMAssay Description:Tested for its activity to inhibit the binding of [125I]gastrin to gastric glands (gastrin) in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article