BDBM50281622 2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-hexanamine; with Hydrochloric acid::CHEMBL545590

SMILES Cc1ccc(SCCCCC(CN)c2ccc(F)cc2)cc1

InChI Key InChIKey=ZSKLAKZZOGGXRK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50281622   

TargetProstaglandin-H2 D-isomerase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50: 2.80E+5nMAssay Description:Compound was tested for its ability to inhibit bovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPhospholipase A2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50: 4.10E+3nMAssay Description:Compound was tested for its ability to inhibit porcine pancreas phospholipase-A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50: 4.87E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article