BDBM50281621 6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl)-1-hexanamine; with Hydrochloric acid::CHEMBL558583

SMILES CC(C)(C)c1ccc(SCCCCC(CN)c2ccc(F)cc2)cc1

InChI Key InChIKey=BDZDUXIRXCUNFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281621   

LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetPhospholipase A2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article