BDBM50281576 (S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-propionylamino]-5-amino-pentanoylamino}-N-((1S,2R)-1-{(1S,2R)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL150719

SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=ZMZJOZFSFHZWRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281576   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50: 130nMAssay Description:The inhibitory constant was evaluated against Endothelin A receptor in rabbit renal artery tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEndothelin-1 receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50281576((S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [125I]ET1 binding to Endothelin A receptor of murine 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article