BDBM50281414 8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5]dec-2-en-4-one; hydrochloride::CHEMBL554415

SMILES Fc1ccc(cc1)C1=COC2(CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=UVZKDPGRNWICJT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281414   

LigandPNGBDBM50281414(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  4nMAssay Description:Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50281414(8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...)
Affinity DataKi:  1.42E+3nMAssay Description:Binding affinity for dopamine receptor D2 in guinea pig striatal membrane using radiolabeled ligand [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article