BDBM50280829 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benzo[e][1,2]thiazin-4-one::CHEMBL57198

SMILES OC1=CN(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)S(=O)(=O)c2ccccc12

InChI Key InChIKey=YELYMKQLVXIVMT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280829   

TargetD(2) dopamine receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50280829(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280829(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 5.40nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280829(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Alpha-1 adrenergic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280829(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against muscarinic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article