BDBM50280826 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2,3-dihydro-benzo[d]isothiazole 1,1-dioxide::CHEMBL57483

SMILES Fc1ccc2[nH]cc(CC3CCN(CCN4Cc5ccccc5S4(=O)=O)CC3)c2c1

InChI Key InChIKey=WABVGRGYPGCSGJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280826   

TargetD(2) dopamine receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Dopamine receptor D2; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against Alpha-1 adrenergic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 100nMAssay Description:Tested for its binding affinity against muscarinic receptor; showed no appreciable affinity at concentration specifiedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50280826(2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1...)
Affinity DataIC50: 1nMAssay Description:Compound was evaluated for inhibition of 5-HT uptake by measuring its ability to inhibit [3H]paroxetine binding to rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article