BDBM50280809 CHEMBL4163811

SMILES CN(C)CCC(=O)N[C@H]1[C@@H](Cc2ccccc12)NC(=O)c1cc2cc(C)ccc2[nH]1

InChI Key InChIKey=IVSKBLPKDGJOST-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50280809   

TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280809(CHEMBL4163811)
Affinity DataEC50:  226nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
LigandPNGBDBM50280809(CHEMBL4163811)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280809(CHEMBL4163811)
Affinity DataIC50: 930nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280809(CHEMBL4163811)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280809(CHEMBL4163811)
Affinity DataEC50:  226nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed