BDBM50280775 CHEMBL4160434

SMILES Fc1ccc2[nH]c(cc2c1)C(=O)N[C@H]1Cc2ccccc2[C@@H]1NC(=O)[C@H]1CCNC1

InChI Key InChIKey=JSQCPIVPEMGCJM-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50280775   

TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280775(CHEMBL4160434)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280775(CHEMBL4160434)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
LigandPNGBDBM50280775(CHEMBL4160434)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280775(CHEMBL4160434)
Affinity DataIC50: 200nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50280775(CHEMBL4160434)
Affinity DataIC50: 189nMAssay Description:Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed