BDBM50280752 CHEMBL4161221

SMILES Cn1cc(\C=C2/CC(CO)(COC(=O)C3CCC(CC3)C(C)(C)C)OC2=O)c2ccccc12

InChI Key InChIKey=KDOMXVVBKAYVDL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280752   

TargetRas guanyl-releasing protein 3(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280752(CHEMBL4161221)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280752(CHEMBL4161221)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCalpha expressed in baculovirus expression system after 5 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280752(CHEMBL4161221)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]PDBu from full length recombinant human PKCepsilon expressed in baculovirus expression system after 5 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMed