BDBM50280655 3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-carboxylic acid methyl ester::CHEMBL268367

SMILES COC(=O)c1oc2c(sc3ccccc23)c1OC(=O)C(C)C

InChI Key InChIKey=STCBJZIZCOASHY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50280655   

TargetCoagulation factor X(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 100nMAssay Description:In vitro concentration of compound required to inhibit 50% of Factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 2.90E+4nMAssay Description:In vitro concentration of compound required to inhibit 50% of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPlasma kallikrein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 7.20E+3nMAssay Description:In vitro concentration of compound required to inhibit 50% of KallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 30nMAssay Description:In vitro concentration of compound required to inhibit 50% of 6 nM thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 2.40E+5nMAssay Description:In vitro concentration of compound required to inhibit 50% of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280655(3-Isobutyryloxy-benzo[4,5]thieno[3,2-b]furan-2-car...)
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine thrombin using Bz-Phe-Val-Arg-pNA as substrate by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed