BDBM50280654 (S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phenyl-acetyl)-pyrrolidine-2-carbonyl]-amino}-pentanoic acid::CHEMBL8108

SMILES CN[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)c1ccccc1

InChI Key InChIKey=CJUOBXSVMSLLKV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50280654   

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280654((S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phe...)
Affinity DataIC50: 20nMAssay Description:In vitro concentration of compound required to inhibit 50% of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProthrombin(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280654((S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phe...)
Affinity DataIC50: 20nMAssay Description:In vitro concentration of compound required to inhibit 50% of 6 nM thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPlasminogen(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280654((S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phe...)
Affinity DataIC50: 500nMAssay Description:In vitro concentration of compound required to inhibit 50% of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetPlasma kallikrein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50280654((S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phe...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro concentration of compound required to inhibit 50% of kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCoagulation factor X(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50280654((S)-5-Guanidino-2-{[(S)-1-((S)-2-methylamino-2-phe...)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro concentration of compound required to inhibit 50% of Factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article