BDBM50280579 CHEMBL4169930

SMILES c1ccc2c(c1)c(c[nH]2)CN3CCC(CC3)NC(=O)CN

InChI Key InChIKey=CVIHXVZLCLPGPP-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280579   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280579(CHEMBL4169930)
Affinity DataEC50: >1.00E+5nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280579(CHEMBL4169930)
Affinity DataEC50: >1.00E+5nMAssay Description:Activation of human SOS1 mediated nucleotide exchange in presence of BODIPY-GDP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)