BDBM50280371 CHEMBL4160779

SMILES COc1ccc(cc1OC)C(=O)Nc1cc(Cl)ccc1-n1cncn1

InChI Key InChIKey=SMVRQKDHIRRQCD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280371   

TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280371(CHEMBL4160779)
Affinity DataIC50: 5.75E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 expressed in HEK cells co-expressing Galpha15 assessed as reduction in L-AP4-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280371(CHEMBL4160779)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGlu8 expressed in HEK cells co-expressing Galpha15 assessed as reduction in L-AP4-induced intracellular calcium flux pret...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280371(CHEMBL4160779)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human mGlu4 expressed in CHO cells co-expressing Gqi5 assessed as reduction in L-AP4-induced intracellular calcium flux pretre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280371(CHEMBL4160779)
Affinity DataIC50: 5.80E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 expressed in HEK cells co-expressing Galpha15 assessed as reduction in L-AP4-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2020
Entry Details Article
PubMed