BDBM50280280 CHEMBL295243::N-{[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]methyl}-N-hydroxy-N'-methylthiourea

SMILES CNC(=S)N(O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12

InChI Key InChIKey=ZKSQQECUHNGXJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280280   

LigandPNGBDBM50280280(N-{[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 400nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetProstaglandin G/H synthase 1/2(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50280280(N-{[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50: 7.10E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article