BDBM50279805 (S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL348012

SMILES CN1CCC=C2[C@@H]1CCc1sc(N)nc21

InChI Key InChIKey=XFJSSDHKIXXJLM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279805   

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 2.92E+3nMAssay Description:Displacement of [3H]spiperone from rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 768nMAssay Description:In vitro binding affinity to Dopamine receptor D2 in rat striatal membranes using D2 antagonist [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro binding affinity to Dopamine receptor D1 in rat striatal membranes using D1 antagonist [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro antagonist binding affinity was determined by displacing the [3H]-SCH- in rat striatal Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article

TargetD(2) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50279805((S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f...)
Affinity DataIC50: 202nMAssay Description:In vitro agonist binding affinity was determined by displacing the [3H]N-propylnorapomorphine ([3H]NPA) in rat striatal Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article