BDBM50279699 2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-3H-quinazolin-4-one::CHEMBL474718

SMILES Cc1nc(Nc2ccccc2)sc1-c1nc2ccccc2c(=O)n1-c1ccccc1C

InChI Key InChIKey=SBZNIFMIWIDIJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279699   

TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50279699(2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50279699(2-(4-Methyl-2-phenylamino-thiazol-5-yl)-3-o-tolyl-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of AP1 expressed in HEK293 cells assessed as inhibition of TNF-alpha-induced transcriptional activation treated 24 hrs before TNFalpha cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed