BDBM50279661 CHEMBL4166065

SMILES OB1OCc2ccc(NC(=S)Nc3ccc(cc3)C(F)(F)F)cc12

InChI Key InChIKey=GVJYFMWJKNXCKE-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50279661   

TargetCarbonic anhydrase 12(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  71nMAssay Description:Binding affinity to human CA12 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  93nMAssay Description:Binding affinity to human CA9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase(Yeast)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  112nMAssay Description:Inhibition of Candida glabrata Nce103 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  275nMAssay Description:Inhibition of Cryptococcus neoformans Can2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  417nMAssay Description:Inhibition of human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  417nMAssay Description:Binding affinity to human CA1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  1.84E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50279661(CHEMBL4166065)
Affinity DataKi:  1.84E+3nMAssay Description:Binding affinity to human CA2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed