BDBM50279650 CHEMBL349816

SMILES [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)NCC(N)=O

InChI Key InChIKey=JWZLANUHRXGDET-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50279650   

TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 35nMAssay Description:Agonist activity at mu-opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically induced contractions after 3 mins post doseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]-CTOP from Mu-type opioid receptor in Sprague-Dawley rat brain homogenate after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 37nMAssay Description:Inhibition of MOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 263nMAssay Description:Agonist activity at delta-type opioid receptor in ICR mouse vas deferens assessed as potentiation of electrically stimulated contractions after 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of DOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50279650(CHEMBL349816)
Affinity DataIC50: 1.25E+3nMAssay Description:Displacement of [H][p-ClPhe4]-DPDPE from delta-type opioid receptor in Sprague-Dawley rat brain homogenates after 180 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2020
Entry Details Article
PubMed