BDBM50279601 CHEMBL4161551

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4CCN(C(=O)Cn5cccn5)c4c3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=HEKLHRGCBLROOS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279601   

TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279601(CHEMBL4161551)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279601(CHEMBL4161551)
Affinity DataIC50: 30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279601(CHEMBL4161551)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279601(CHEMBL4161551)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279601(CHEMBL4161551)
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed