BDBM50279594 CHEMBL4166319

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4CCN(C(=O)CN(C)C)c4c3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=OSHAGQCZZMYWEP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279594   

TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279594(CHEMBL4166319)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279594(CHEMBL4166319)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279594(CHEMBL4166319)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed