BDBM50279592 CHEMBL4166187

SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N3CCC(CN4CCN(C)CC4)C3=O)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=VPZDWQHUUTZTSQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279592   

TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279592(CHEMBL4166187)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279592(CHEMBL4166187)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279592(CHEMBL4166187)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279592(CHEMBL4166187)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant PDGFRbeta (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279592(CHEMBL4166187)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2020
Entry Details Article
PubMed