BDBM50279271 CHEMBL4168907

SMILES CN[C@@H](C)C(=O)N(C)[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1cccc(OCCOCCOCCNC(=O)C2CCN(C2)c2ncc(cc2-c2ccn[nH]2)C(=O)Nc2ccc(OC(F)(F)Cl)cc2)c1

InChI Key InChIKey=FYLZMKXSUQIMJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50279271   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP1 (Leu250 to Gly350 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged XIAP (Asn252 to Thr356 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant human His-tagged full length ABL1 allosteric site expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50279271(CHEMBL4168907)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged cIAP2 (Gln238 to Ser349 residues) expressed in Escherichia coli by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2020
Entry Details Article
PubMed