BDBM50279240 2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1Hpyrazol-3-yl]-3,5,5-trimethyl-3,5-dihydro-imidazol-4-one::CHEMBL522904

SMILES CCc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C1=NC(C)(C)C(=O)N1C

InChI Key InChIKey=USNWJHORIWPSKG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279240   

TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279240(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-e...)
Affinity DataIC50: 33.8nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279240(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-e...)
Affinity DataIC50: 4.33E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50279240(2-[5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-e...)
Affinity DataEC50:  65.5nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in HEK293 cells assessed as inhibition of CP-55940-stimulated Eu-GTP bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed