BDBM50279227 CHEMBL4167203

SMILES OC(=O)c1[nH]c2cc(Cl)ccc2c1C1N(Cc2cc(F)c(F)c(F)c2)C(=O)CCCCCCCCCCCCCCNC1=O

InChI Key InChIKey=UGQIEUVQPKDGJY-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50279227   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50279227(CHEMBL4167203)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to recombinant N-terminal domain of human 15N-labeled MDM2 (1 to 118 residues) at Arg29 residue expressed in Escherichia coli BL21-C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50279227(CHEMBL4167203)
Affinity DataKi:  140nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from recombinant human N-terminal MDM2 (1 to 118 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2020
Entry Details Article
PubMed