BDBM50279138 CHEMBL4164427

SMILES COc1cc(ccc1-n1cnc(C)c1)-c1noc2C(CCCc12)NCc1ccc(F)cc1

InChI Key InChIKey=VNHURZWDNQYTCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279138   

TargetPresenilin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50279138(CHEMBL4164427)
Affinity DataIC50: 130nMAssay Description:Modulation of gamma-secretase (unknown origin) expressed in HEK293 cells harboring SCP99-Lon mutation assessed as reduction in Abeta42 production aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2020
Entry Details Article
PubMed