BDBM50279106 4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one::5-(4-phenoxybutoxy)psoralen::CHEMBL444449

SMILES O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1

InChI Key InChIKey=KINMYBBFQRSVLL-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50279106   

LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of cloned Kv1.3 channel expressed in mammalian cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 potassium channel expressed in mouse L929 cells by whole cell patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human Kv1.3 ion channel expressed in CGE22 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of human Kv1.5 ion channel expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 1(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Kv1.1 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 4(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 6(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 2(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human Kv1.2 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed