BDBM50278984 CHEMBL4168710

SMILES COc1ccccc1CNCCCCCOC(=O)Nc1cc(Cl)nc(Cl)c1

InChI Key InChIKey=NXDHXDOGBRDRPD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278984   

TargetAcetylcholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataIC50: 6.16E+3nMAssay Description:Inhibition of human serum AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50278984(CHEMBL4168710)
Affinity DataKi:  288nMAssay Description:Mixed inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured from 0.5 to 1.5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details Article
PubMed