BDBM50278704 CHEMBL503418::N7-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-N2-(4-((4-methylpiperazin-1-yl)methyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES CN1CCN(Cc2ccc(Nc3nc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4s3)cc2)CC1

InChI Key InChIKey=ANGBZYNNANAOBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278704   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278704(N7-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-N2-(4-((...)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed