BDBM50278703 CHEMBL470391::N7-(3-ethynylphenyl)-N2-(4-(morpholinomethyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES C#Cc1cccc(Nc2ncnc3nc(Nc4ccc(CN5CCOCC5)cc4)sc23)c1

InChI Key InChIKey=VLZLKHGQUWVLCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278703   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278703(N7-(3-ethynylphenyl)-N2-(4-(morpholinomethyl)pheny...)
Affinity DataIC50: 43nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed