BDBM50278702 CHEMBL471058::N7-(3-chloro-4-fluorophenyl)-N2-(4-((2-ethyl-1H-imidazol-1-yl)methyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES CCc1nccn1Cc1ccc(Nc2nc3ncnc(Nc4ccc(F)c(Cl)c4)c3s2)cc1

InChI Key InChIKey=YWBUMHFXOAMBLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278702   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278702(N7-(3-chloro-4-fluorophenyl)-N2-(4-((2-ethyl-1H-im...)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed