BDBM50278652 CHEMBL511637::N7-(3-chloro-4-fluorophenyl)-N2-(4-(morpholinomethyl)phenyl)thiazolo[4,5-d]pyrimidine-2,7-diamine

SMILES Fc1ccc(Nc2ncnc3nc(Nc4ccc(CN5CCOCC5)cc4)sc23)cc1Cl

InChI Key InChIKey=ZUSZRGNCVDXEAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278652   

TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50278652(N7-(3-chloro-4-fluorophenyl)-N2-(4-(morpholinometh...)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed